Biosafety develops, updates and implements a comprehensive biological safety program including Institutional biosafety policies, guidelines and procedures. Biosafety identifies biological hazards in UCI campus, mainly associated with biological research, suggests methods to mitigate associated risks and serves as a resource for Federal, State and Local regulations and safety guidelines.
- Institutional Biosafety Committee (IBC)
- Cal/OSHA Bloodborne Pathogens (BBP)
- Cal/OSHA Aerosol Transmissible Diseases (ATD)
- High Containment Laboratory Program
- BUA/IBC application Prereview
- Biosafety site assessments (BSL2 and BSL3) and consultations
- Research specific training: Hazard identification, risk management and infectious agent specific discussion
- SOP development
- Exposure Control Plan development
- Biological research-related incident investigations and response
- Preparing CDC and USDA import/ transport permit application
- Preparing for CDC and USDA inspection
- Lab certification for NIH or other grantors
- ATCC BSL2 upgrade approval
NIH Recombinant and Synthetic nucleic acid guidelines
Federal Select Agents and Toxins Program
CAL/OSHA Bloodborne Pathogens (BBP) Standard
CAL/OSHA Aerosol Transmissible Disease (ATD) Standard
CDC Biosafety in Microbiological and Biomedical Laboratories, 5th Edition
Microtome/Cryostat-Need cut resistant gloves? Contact email@example.com)
For all BSL2 and higher work, BSCs must be certified annually. Please contact TSS at 1-800-877-7742 to certify your BSC. The lab will be charged by TSS for the certification.
Please contact TSS at 1-800-877-7742 to decontaminate the BSC. After decontamination, submit an EH&S clearance request form.
Please contact your EH&S Coordinator to obtain a biological spill kit.
Biosafety provides consultation on how to set up BSL2 and higher containment labs. Please contact firstname.lastname@example.org
UCI follows the containment requirements included in the CDC Biosafety in Microbiological and Biomedical Laboratories (BMBL, 5th edition) and NIH Guidelines for Research Involving Rcombinant or Synthetic Nucleic Acid Molecules. Please check UCI Biosafety Manual for additional information.
Established human cells lines fall under Cal/OSHA Bloodborne Pathogen (BBP) standard. Other examples are: human blood, tissues and organs, non-human primate cell lines, Lentivirus, Hepatitis B virus. As per the standard annual BBP training (via UCLC) and annual review of BBP-ECP is required.
Adenovirus is an aerosol transmissible pathogen under Cal/OSHA Aerosol Transmissible Disease (ATD) standard. Other examples are Herpes Simplex Virus, Influenza virus, Streptococcus spp. (Group A), SARS-Coronavirus. As per the standard annual ATD training (via UCLC) and annual review of ATD-ECP is required.
Please visit the EH&S SOP Library to obtain an SOP template.
Bunsen burners are not allowed inside the BSC. IBC’s position on Bunsen burners. Contact email@example.com to obtain a on-demand burner.
Please see the IBC’s guidance on the safe handling of human cell lines.